No. But beware, it can be fatal when ingested in excess.
Rue is a plant mentioned in the Bible. Luke 11:42 enunciates the importance of this herb in the Palestinian region, as Jesus refers to a tithe on rue. Because the Bible describes the period from about a thousand years before the birth of Jesus, it is possible that rue grew wild then, with cultivation starting around the time Jesus was born. The Talmud describes rue as a kitchen herb that grows in the wild.
Ruta graveolens is the botanical name of rue. Rue leaves contain rutin, an antispasmodic flavonoid. Rutin has a beneficial effect on the circulatory system. It is recommended in the herbal treatment of insomnia, headaches, nervousness, abdominal cramps, and renal trouble. Traditionally, it is regarded as a contraceptive and a well-known emmenagogue. The most frequent use of the plant has been to induce abortion.
The plant may be part of sedative and hypnotic herbal preparations. Since Pollio et al. (2008) discovered that rue can be fatal if ingested, its use as a medicinal and culinary herb has diminished. Significant temporary immobility of spermatozoa without any adverse effects on other sperm characteristics was observed in R. graveolens L. aqueous extract trials conducted on rats. Thus, the plant has potential use as a male contraceptive.
You can read more on rue here.