No. But beware, rue can be fatal when ingested in excess. Ruta graveolens is the botanical name of rue. Rue leaves contain rutin, an antispasmodic flavonoid. Rutin has a beneficial effect on the circulatory system. It is recommended in the herbal treatment of insomnia, headaches, nervousness, abdominal cramps, and renal trouble. Traditionally, it is regarded as a contraceptive and a well-known emmenagogue. The most frequent use of the plant has been to induce abortion.
The plant may be part of sedative and hypnotic herbal preparations. Since Pollio et al. (2008) discovered that rue could be fatal if ingested, its use as a medicinal and culinary herb has diminished. Significant temporary immobility of spermatozoa without any adverse effects on other sperm characteristics was observed in R. graveolens L. aqueous extract trials conducted on rats. Thus, the plant can be used as a male contraceptive.
The Greeks also valued the herb. In his Materia Medica, the Greek physician Dioscorides states: “Boiled with vinegar it easeth pains, is good against the stitch of the side and chest, and shortness of breath upon a cold cause, and also against the pain in the joints and huckle bones … The juice of Rue made hot in the rind of pomegranate and dropped into the ears, takes
away the pain of thereof … That Rue put up in the nostrils stayeth bleeding.” He also describes two kinds of rue: a mountain variety and a strong-smelling garden variety. The garden plant was tithed and cultivated even then. Soranus, a gynecologist in second-century Greece, described it as a potent abortifacient.
The Romans grew rue around their temples to Mars. It was considered sacred to Diana, the moon goddess, and Aradia, purported in legend as her daughter. Roman philosopher and healer Pliny mentions rue 80 times in his work. He states, “when notwithstanding it is of power rather procure bleeding, through its sharp and biting quality. The leaves of Rue beaten and
drunk with wine are an antidote against poisons, as Pliny saith.” Pliny also reported that, in ancient Rome, painters and engravers used rue to sharpen and preserve their eyesight.
You can read more on rue here.