Obesity is a complex disease. People suffering from obesity may not get to lose weight by only eating less and doing exercise. Let me present some scientific facts that will illustrate the complexity of this disease.

An adverse prenatal environment may induce long-term metabolic consequences like obesity and insulin resistance. Inappropriate growth during pregnancy or lactation may lead to an increased risk of developing obesity. The mother and through her, the child gets impacted by related metabolic actions. (Vickers, 2007 (https://journals.lww.com/co-endocrinology/Abstract/2007/02000/Developmental_programming_and_adult_obesity__the.5.aspx))

Food consumed by the mother during the pregnancy period plays a critical role in fetal development. Understanding the role of diet and nutrition in modifying genetic expression is complex. Food choice, diversity of nutrient intake, individual genetic differences, intestinal environment, physiological action in an individual’s intestine, and impact on the individual from the use of new technologies by consumers – all play a part in obesity expression. (Cobiac, 2007 (https://www.karger.com/Article/Abstract/107065))

Epigenetic marks or imprinting affect gene expression without changing the DNA sequence. Epigenetics is responsible for the increased susceptibility of an individual to obesity. External exposures during critical development periods can alter the profile of epigenetic marks and result in obesity. (Herrera et al., 2011 (https://www.ncbi.nlm.nih.gov/pubmed/21466928))

Epigenetic markers are responsible for obesity at birth. Several of these are modifiable by changing the fetus’s exposure to the uterus and undertaking lifestyle changes in adult life. Interventions in postnatal life can modify unfavorable epigenetic profiles. (Van Dijk et al., 2015 (https://www.ncbi.nlm.nih.gov/pubmed/24566855))

It is vital to understand the relationship between epigenetics, nutrition, and obesity. We then require to understand underlying mechanisms. It is only then we should begin to use supplements, medication, etc., to tackle obesity.

You may not get results if you focus only on diet and exercise.

Book reference:

Natural Solutions for Obesity

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