A non-invasive skin treatment or a minimally invasive method is used to correct the skin and its condition cosmetically. These include:

  1. Needle-free mesotherapy
  2. Application of ultrasound
  3. Oxygen infusion
  4. Chemical peels
  5. Micro-needle mesotherapy

Ultrasonic Waves- A non-invasive skin treatment

Ultrasound waves with a frequency of 20,000 Hz widen the intercellular space in the skin, allowing for better penetration of active substances. Deep skin massage performed by the ultrasonic device stimulates cells to regenerate. The frequency setting of the wave is raised for better penetration. The therapy helps smooth wrinkles and improves skin tone.

Microfocused ultrasound (MFU) can be focused on deep skin tissue where the temperature briefly reaches greater than 60 degrees Celsius. Heat application causes collagen fibers to become denatured, contracting and stimulating de novo collagen. High-resolution ultrasound imaging (MFU-V) is used. The treatment tightens and lifts sagging facial and neck skin, and improvements in the appearance of wrinkles were achieved. Fabi, S.G. (2015), MacGregor, J.L., et al. 2013. The procedure significantly improves the mid and lower face sagging aesthetics. MFU treatments can activate deeper tissues without causing injury to the skin (Khan U. et al., 2021).

Oxygen Infusion – a non-invasive skin treatment

Oxygen infusion treatment can help with signs of aging, such as wrinkles and uneven tone. Oxygen infused into the skin re-energizes cells and promotes collagen production, helping restore skin volume, remove wrinkles, and create new skin cells. Treatments include infusing a medicated serum with pure oxygen into the deepest layers of the skin. A machine is used to apply pure pressurized oxygen to the skin.  Oxygen infusion can cause temporary redness, puffiness, or mild swelling in people with sensitive skin.

The procedure is considered non-medical. Nothing is injected into the body, and no chemicals are used. It is done by an aesthetician in a spa. After cleansing and exfoliating the skin, the spa delivers a stream of high-pressurized oxygen to the skin’s surface. Serums, usually containing hyaluronic acid, are applied to the face. The treatment is expected to take around thirty minutes to an hour. Makeup can be directly applied after the treatment.

Oxygen infusions are provided by devices such as X2 Exea, which allow the flow of pure oxygen (up to 96 percent purity) to reach the superficial layer of the skin, from where the deeper layers absorb it. Oxygen improves cellular metabolism, accelerates healing processes, reduces skin irritations, and is antibacterial. (Bennardo, L et al., 2018) Anecdotally, it is claimed that oxygen infusion makes the skin appear brighter and healthier, but scientific evidence supporting these claims has not yet emerged.

Chemical peeling

Chemical peeling is a popular skin-surfacing treatment that uses chemicals to remove lesions caused by aging or trauma. Surface peels separate the dead layer of cells from the skin. Chemical compounds used include glycolic acid, mandelic acid, pyruvic acid, salicylic acid, trichloroacetic acid, retinoids, and Jassner’s solution.

Chemical peels have been used to resurface and rejuvenate since and before Biblical times. Eber’s Papyrus, dating back over 3500 years, refers to using animal oils, salt, milk, and alabaster to condition the skin. Cleopatra bathed in sour donkey’s milk to keep her skin soft and youthful. Milk and bathing were popular in ancient Rome and India. The Indian tradition of washing the body with sour yogurt continues today.

The science behind many of these skin remedies was unknown to ancient man. We now know that the skin appears soft and fresh due to alpha hydroxy acids (AHAs), lactic acid in sour milk, and tartaric acid in wine. Today, the same agents are used in chemical peels.

Chemical peeling is a treatment of choice for numerous pigmentary and scarring disorders arising in dark skin tones. Robert, W.E. (2004). The peel procedure is common for all skin chemical peeling agents. Still, it is important to understand the specific characteristics of each agent to decide which to use for each patient (Zakopoulou N. et al., 2006).

Chemical peels are classified as superficial, medium, and deep peels. Superficial peels of alpha-hydroxy acids and lipo-hydroxy acids exfoliate the skin. Peels with medium-depth agents, such as trichloroacetic acid, cause epidermal regeneration. Deep peels using trichloroacetic acid above 50 percent or phenol-based formulations reach deeper and induce dermal regeneration. (Fischer, T.C et al.,2010)

Superficial peels penetrate only the epidermis and treat acne, melasma, dyschromias, photodamage, and actinic keratoses. Medium-dept peels penetrate deeper and are used for dyschromia, multiple solar keratoses, superficial scars, and pigmentary disorders.  Deep peels are for facial resurfacing. (Rendon, M. I et al., 2010)

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