Nature has several cancer-protecting compounds. Fruits, vegetables, soybeans, colored flowers, and plant-derived beverages, such as green tea, wine, and cocoa-based products, are the primary sources of flavonoids. These compounds exhibit antioxidant and anticancer properties. (Kopustinskiene, D M et al, 2020) Compelling data from laboratory studies and human clinical trials have shown that flavonoids have important effects on cancer chemoprevention and chemotherapy. (Ren, W et al., 2003)
Flavonoid preparations are marketed as herbal medicines or dietary supplements. These induce tumor cell death. These are considered safe. (Galati, G et al., 2004) A review of the anti-cancer properties of flavonoids in the treatment of mammary and prostate cancer has shown that these compounds play a crucial role in cancer prevention. (Chahar, M K et al., 2011)
The antioxidant and anti-inflammatory properties of flavonoids from Citrus plants have shown the anticancer properties of these compounds. (Benavente-Garcia, O et al., et al 2008). These compounds have been shown to interfere with cancer initiation, promotion, and progression. (Ravishankar, D. et al., 2013)
Cancer-protecting compounds – Epigallacotechin – 3- gallate
Camellia sinensis is the botanical name of the tea plant, which is valued for its young leaves and buds, which are used to make tea beverages. The shrub’s natural habitat is parts of Northeast India, China, and East Asia. Some tea is also grown in Kenya and South America.
Green tea is made from freshly plucked leaves cooked to preserve the green color and prevent oxidation. This process helps maintain a higher concentration of chlorophyll, polyphenols, and antioxidants. Chinese tea is often pan- or wok-roasted, while Japanese tea is typically deeply steamed. Written records indicate that the cultivation of green tea dates back to the Han Dynasty in China (206-220 AD).
Green tea has anticancer and anti-inflammatory properties. The main antioxidant agents are catechins, which include epicatechin, epigallocatechin, epicatechin gallate, and epigallocatechin gallate. Among these, epigallocatechin gallate exhibits the most potent anti-inflammatory and anticancer potential. Green tea catechins effectively prevent the development of lung, breast, esophageal, stomach, liver, and prostate cancers. However, green tea should not be used as a substitute for standard chemotherapy (Musial, C et al., 2020). (Musial, C et al., 2020)
An inverse correlation between green tea consumption and various cancers, including urinary bladder, esophageal, stomach, rectal, and lung cancers, has been noted. Bushman, J.L. (1998). Studies show that green tea consumption, not black tea, helps prevent human cancers. (Jankun, J et al., 1997). Tea catechins, including epigallocatechin-3-gallate (EGCG), help inhibit gene expression that triggers cancers. (Rashidi, B et al., 2017) It helps prevent cancer. (Cabrera, C. et al., 2006; Azam, S. et al., 2004) Catechins help quench free radicals, reducing oxidative stress and exhibiting pro-oxidant effects against carcinogenic action. (Lambert, J D et al., 2010)
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