Tinospora cordifolia plant is a climbing deciduous shrub found growing in tropical South Asia and China. It is a hardy plant that grows on acidic to alkaline soils. It is a well-known medicinal plant in Ayurveda.
The plant, in conjunction with other herbs, is extensively used in Ayurveda to treat a range of ailments. Its immunomodulatory and cytotoxic properties that are relevant to cancer treatment have been extensively documented. But as in other herbs, formal clinical trials that would unequivocally validate the anticancer potential of the herb are lacking.
Cyclophosphamide is an anticancer drug that has toxic side effects. In mice studies, Tinospora cordifolia was observed to mitigate the side effects caused by cyclophosphamide (Hamsa & Kuttan, 2012).
The radioprotective role of the plant has been observed in animal trials. The plant was observed to effectively kill cells in in vitro trials conducted by Jagetia et al. (1998). The effect of the plant extracts was observed to be comparable or better than doxorubicin, which is a chemotherapy medicine.
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